May 27, 2006

PCOS

This Discussion Forum is for discussion of PCOS (Polycystic Ovary Syndrome), a disorder involving insulin resistance that may affect women.

Please review and follow our usual ground rules, at Ground Rules. (To share your thoughts, use the "Comments" link immediately below.)

Bill the diabetesdoc
info@diabetesmonitor.com

Diabetes.Blog.Com is a blogcompanion to our main website, the Diabetes Monitor, which you can find at http://www.diabetesmonitor.com





Posted by Bill the diabetesdoc at 00:00:02 | Permanent Link | Comments (74) |
Comments
1 2
1 - Bill,

Thank you for starting this forum! What a great heart your have for the needs of others. So many women with PCOS suffer from insulin resistance, weight gain, and eventually type 2 diabetes.

I'd love to open potential discussion with a common rant among us "Cysters" -- weight!

I am a 9-year-verteran low-carber (50 grams or less per day). Low carb took off 150+ lbs and kept it off until recently. Now, even on low-carb the weight is coming back as are all the old "fun" PCOS problems like hirsutism and scalp hair loss.

I'd like to stay low-carb but have type 2 diabetes and not eating carbs is causing my blood sugars to crash a lot. I am interested in hearing how other women have had weight management success (with PCOS or type 2) on a low glycemic or other plan.

I am afraid to add carbs back into my diet because I gain weight rapidly above 50 grams per day. But clearly I am not eating enough to counter the effects of insulin overproduction. (I am on 2000 mg per day of Glucophage and it is not helping.)

Lahle (Comment this)

Written by: Lahle at 2006/05/27 - 15:31:45
2 - I am also PCOS and Type II - what a struggle to deal with both! (Comment this)

3 - Lahle:

I can't even look at a carb without my BG going up! I have to stay within 10-15 carbs a meal or I go up horribly. My BG is not incontrol yet - I have been on the Spit for a little over a month and have lost 23 pounds but my BG's have not seen a huge difference. I am hanging in there but watch what I eat very carefully. So I am with you, Sister! (Comment this)

4 - Some messages from our sponsor:

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Many thanks, from Steph & Bill Quick

 

 (Comment this)

Written by: Steph & Bill Quick at 2006/05/28 - 07:46:28
5 - Lahle:

It is because of PCOS gynecological symptoms that I ended up at an endo several years ago. I have been on metformin since that time.

I've never met the criteria for an official T2 diagnosis. My FBGs are impaired (slighly over 100) but never over 126 and my A1Cs were also creeping up (but have never been over 7).

At my appt. in January, my endo felt that things were certainly NOT moving in the right direction and I agreed. He suggested Byetta as a method of keeping the situation from getting any worse. It took 2 very detailed letters to my HMO to get them to cover. He specifically addressed my PCOS and the need to regulate my blood sugars and lose weight. Of course, the HMO first wanted me to use sulfonylureas which are likely to cause weight gain.

Long story short...I've been on Byetta since January. On my 3 month blood work, my AIC was down and my FBG was normal. I've lost nearly 40 lbs. Regarding the weight loss...my endo and I share the opinion that Byetta helps, but it is mainly my own dietary and exercise changes that have contributed. Also, I am very overweight so at least initially, it's been faily easy to lose. (Comment this)

Written by: Henley at 2006/05/28 - 10:14:05
6 - I hope y'all don't mind if I come here and ask a question. I don't have PCOS (I guess I don't) because I'm 58 and past menopause but I am type 2 and extremely insulin resistant. Last month my doctor checked my insulin level - 3 hours after a breakfast of less than 6 carbs and it was 26 with anything over 17 being high.
I started byetta 2 weeks ago and my blood sugar is running under 100 all the time.
My concern - will the byetta cause me to make even more insulin?
Besides the inability to lose weight, the thinning of my hair bothers me a lot. I'm pinning a lot of hope on byetta! (Comment this)

Written by: Marion at 2006/05/28 - 16:35:41
7 - Marion:

I was diagnosed with PCOS in my early 20's so you certainly can have it and not know it unless you know the symptoms. There is no test for PCOS. I have several very small cysts on my ovaries - hence PCOS and I met all the criteria for diagnosis. I am now 47 and have had to be on birth control ever since diagnosis to regulate my periods. I was diagnosed with Type II in my mid-30's but I believe I had the symptoms in my late 20's. (Comment this)

8 - I have PCOS also but do not take anything for it. I have been on Byetta since March and I have not lost any weight. I am wondering if I need to be on metformin also. Almost everyone else that is taking byetta is taking another med for their diabeties. I also ordered the free travel pack and was reading the information in the book that came along with it and it indicated that Byetta worked best when used with metformin. Could it be that we need to used it in combination? I am not going to a specialist just a general practioner. I need to get quiet a bit of weight off. My daughter is 16 and she has PCOS and her weight is very high too. I am wondering what would possibly help her also. She is so young to be so heavy and I would really like to find something that would helps us. As a family we have been working on better eating habits this year. We have made alot of changes. Any help would be greatly appreciated. Thanks (Comment this)

Written by: Sylvia at 2006/05/29 - 11:57:19
9 - Sylvia - You and your daughter would most likely be helped by taking metformin with the byetta. And, probably the most important thing for treating PCOS is a very low carb diet. (Comment this)

Written by: Marion at 2006/05/30 - 07:59:39
10 - Sylvia:

I might suggest you and your daughter see a endo. I didn't get the proper diagnosis and help until I started seeing my endo. He is the one who explained a lot about the physical changes I had in relation to PCOS. However, I didn't help myself with the T2 (dx 2/06) but for your daughter it maybe able to help her in the long run. My daughter who will be 21 this summer is overweight and I believe to have PCOS. It trying to manage it with weight loss, especially with the diabetes in mine and my husband's family. I told her when she is ready for an endo let me know. I don't want her to wait but she is having denial about PCOS but I know if she can loose weight and cut out carbs that will help her until she is ready. Good luck

Toni (Comment this)

11 - SYLVIA:

I also would suggest an endo for both you and your daughter.

Looking back, it is now clear that my PCOS symtoms began during my teen years. However, it was not until my late 20's that I was diagnosed. By then, my fertility was gone and other body systems were already being impacted. It was easy to ignore throughout my teens and early 20's because I had no acute problems. Weight was always an issue for me, but became more so during that time. I never had regular periods--and as a teenager and young adult, I surely didn't miss them! I wasn't about to go to a doctor to find a way to get something I didn't miss. By the time I sought treatment, my body had been too out of whack for too long to regain fertility without very invasive procedures.

It's a matter of utmost important for her general heatlh and her reproductive health if she wishes to have children in the future. (Comment this)

Written by: Henley at 2006/05/30 - 12:22:34
12 - I was diagnosed with PCOS, which went by the name of Stein-Leventhal Syndrome in those days, when I was 18 and still hadn't started menstruating. The endocrinologist gave me an injection to start my periods and put me on birth control pills and a thyroid medication. That combination helped me lose weight for the first time in my life, and I was able to easily control my appetite. I stopped taking both meds in my early 40s, and was able to maintain the weight loss and lack of symptoms like hirsuitness and acne, etc., for several years, but slowly the weight started to creep back on and my level of testosterone started to rise. The endo then put me on Aldactone which, through its diuretic action, lowered my level of testosterone and basically got rid of any of the annoying symptons of the syndrome. I still take it today, along with Byetta and Glucophage.

Back when I was first diagnosed with T2 in 1999, my endo said they were just starting to put their PCOS patients on Glucophage even though they were not testing out in the diabetes range. Today, they are putting a number of them on Glucophage and Byetta. I wish I had those two drugs in my arsenal all those many years ago. (Comment this)

13 - Lorrie T2 (1999) Byetta (12/05) Glucophage 1000mg (2x) Aldactone 50 mg (2x) Diovan 140 mg, Nexium 40 mg (2x) Vytorin, Hi-
I'm on Byetta, Glucophage and was just put back on Aldactone after a 5 year hiatus because of recurring PCOS symptoms like hirsutism and hair thinning. I have just gone through menopause but still have PCOS, confirmed by my lab tests. I was wondering for those on Byetta and Aldactone, if there was a suggested timing for when to take them. Is an hour apart enough? I used to take the Aldactone in the morning.

Anyone else on Aldactone for hirsutism here? (Comment this)

14 - Deb in NJ Type 2 since 10/11/01,Byetta-5 (5/19/06),Glucophage XR 1500mg./bedtime, Hi Deb,
As I mentioned on the Byetta Blog, I moved my Aldactone and other meds to lunch and late night snack, I've been taking Aldactone for 10+ years, and it's helped with hirsuitism and other side effects. I've used electrolysis for years, but once I started on Aldactone, I found I only needed to go twice a year. The recent weight loss with Byetta is beginning to significantly lower my testosterone level, too, which helps reduce the side effects of PCOS. (Comment this)

15 - Hi LORRIE,
I really appreciate your responding.
Aldactone worked great for me for over 10 years too, but when I went on Glucophage, my gyno insisted that I wait and see if that would take care of the PCOS hirsutism. It didn't. I had laser treatments to deal with the facial hair, but when my hair started to thin, I just went through menopause, I figured I'd get back on it and give it a try. My labs showed that my testosterone was in normal limits, but I am just very sensitive to it. My last lab also showed that despite menopause, I still have PCOS because my DHEA levels were high. That's great that you only need to go twice a year for electrolysis. I went for years, but really like the laser treatment much better. (Comment this)

16 - well.... I'm not sure, but im in 90% sure that I might have PCOS.Ever since I got my period 5 years ago, it's NEVER been regular and well I've always been overweight but never really passed the 170 lbs until i got my period, I gained 70 pounds in less than a year. I can't loose them! I've actually gone to the gym for months and worked out so much and ate healthy but I only managed to loose 10 lbs. I really agree with Silvia here, to go to the DR. But it's the people around me that say "you are lucky you don't get your periods!" But I DON'T feel lucky. Ever since I learned about PCOS i've been afraid I have it. I have all the signs. The failed periods, acne, overweight, dark discoloration of the skin, thining hair, and hair places where there should really be none.Imagine I HAVE to shave EVERY day, my legs really, facial hair also! It grows SO rapidly. I am postponing going to the DR till August... When i have a nice vacation in a week and calm down and have enough courage to face my troubles (Comment this)

Written by: nidia at 2006/07/09 - 18:33:57
17 - nidia, NIDIA:
There are some effective treatments for PCOS which can help resolve a number of the problems you're experiencing. When I was first diagnosed at age 18, the endocrinologist put me on the birth control pill and a thyroid medication. For the first time in my life, I actually got my period and it was regular. I immediately started to lose weight, the weight I could never seem to shed although I never overate, was an athlete, etc. Those two meds kept me in good shape for about 15 years. Now, I take Aldactone which helps to lower my level of testosterone and prevents the problems with acne, excess hair....but not weight. Byetta and Glucophage are doing the trick for weight control so my weight is in the normal range, my blood sugars are in the low 90s when fasting, low 80s two hours after meals, and I have none of the frustrating symptons of PCOS.

There are medications out there to help you. You shouldn't have to go through all you're experiencing now. (Comment this)

18 - Thanks for answering Lorrie. I know what you mean. I mean even though I am overweight I am very active. I love running around and walking alot, cleaning my house is very entretaining, I sweat and sweat and feel great but no weight comes off. Luckly I've arranged an appointment with a Gyno. to see what's going on. Hopefully if I do get diagnosed I'll finally get that of my mind. (Comment this)

Written by: Nidia at 2006/07/12 - 22:11:55
19 -
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Written by: Bill the diabetesdoc at 2006/07/13 - 06:46:31
20 - Lahle, My endo said to keep my carbs at 90, but no less. I just try to make my carbs glysemic index friendly. I too gain weight very easy. I also have type 2 diabetes and thyroid failure so my body is a food storage compartment. (Comment this)

Written by: Brenda Whitten at 2006/07/24 - 11:50:59 in reply to: 1
21 - Sylvia, Have you had any luck in the weight loss yet ? (Comment this)

Written by: Anonymous at 2006/07/28 - 12:06:13 in reply to: 8
22 - Marion, Marion- Have you been tested for PCOS at all? I wasn't diagnosed until my 50s(I actually saw a TV show and then told my MD about it who in the past had not connected the dots with me- even though she was an expert in PCOS!) and after I had developed many of the complications Type II diabetes, hair loss, hirsutism, acne, weight gain, etc. I was never infertile so in the early years there was nothing to alert anyone. But I did have slowly progressing hair loss, weight gain since my early 20s, and acne into my 40s. (Comment this)

Written by: Marie Whitehead at 2006/08/05 - 13:49:15 in reply to: 6
23 - Lahle, Lahle,

I see an endo and started seeing a nutritionist in July. My Nutritionist recommends I eat 62 g Carbs, 16 g Fat, and 25g protein at every meal. So far since starting this on 7/18/06 I have lost 12 lbs. This was a huge change from my low carb or even regular diet eating habits. And I found that I am less hungry throughout the day. I just started Byetta on 8/3 and am struggling to even eat as much as they've recommended. My weight started at 276/ current 264 so your needs may be different. In the past I lost 60 lbs doing the low carb diet (lost to below 200lbs, but gained all that back and more when I started eatting more carbs.) I found that while doing the low carb I was exhausted all the time and my hair fell out, and just said I wasn't going to put myself through that anymore.

Hope this helps. Summer in TN


By the way, I am also taking meds for my PCOS and TYpe 2 DM. Metformin 1000mg am and 1500mg pm, 100mg Spironolactone BID, Yaz, and 5mcg Byetta. (Comment this)

Written by: Summer at 2006/08/06 - 01:51:41 in reply to: 1
24 - I feel for you and your daughter! I was diagnosed (incorrectly I think) at 16 with adrenal hyperplasia. I have taken Birth Control and other meds since then. I was never sucessful at losing weight until I tried low carb and phen fen, and that left me exhausted, with hair falling out, and heart valve damage. After I stopeed the Phen fen and went back to eatting regular, all of the weight plus some came back on. I am active and exercise regularly.

I was finally diagnosed with PCOS and just recently Type 2 Diabetes. (I am in my late 20s.) I have been connected with a great endocrinologist and nutritionist who just started me on a healthier diet and Byetta. It's only been a couple of weeks since the new nutrition, but I have lost weight and am very hopeful.

I so wish I had gotten the right information in my teens and I would have spent the last 10 years overweight, having poor body image, and building to type 2 diabetes. There are so many health risks if the PCOS isn't treated. Not to mention the infertility. Now my doctor says if I can lose the weight The may be able to safely do fertility treatments and I might be able to get pregnant.

Just don't take no for an answer with your doctors and get her the help she needs.

My Dr. Said with the PCOS you can't do it with Diet and Exercise alone and that everthing feeds on itself. The more you weight the more Insulin Resistant you are to more you'll weigh. Not to mention the increased testosterone and all the other side effects.


Written by Summer in TN. Taking meds for my PCOS and TYpe 2 DM. Metformin 1000mg am and 1500mg pm, 100mg Spironolactone BID, Yaz, and 5mcg Byetta. (Comment this)

Written by: Summer at 2006/08/06 - 02:09:27
25 - Re: to 13

"Anyone else on Aldactone for hirsutism here?"

I am on Aldactone/ Spironolactone 100mg BID, it helps with the chest, but not with the face for me.

By the way, I am also taking meds for my PCOS and TYpe 2 DM. Metformin 1000mg am and 1500mg pm, 100mg Spironolactone BID, Yaz, and 5mcg Byetta. (Comment this)

Written by: Summer at 2006/08/06 - 02:12:29
26 - Lorrie T2 (1999) PCOS Byetta (12/05) Glucophage 1000mg (2x) Aldactone 50 mg (2x) Diovan 140 mg, Nexium 40 mg, Vytorin, I WAS WANTING TO KNOW ABOUT PCOS WITH BYETTA DRUG I WOULD LIKE TO TRY IT BUT MY DOC HAS NEVER GAVE THIS TO SOME ONE WITH PCOS AND NOT LEVEL 2 YET. BUT I HAVE A RAISED LEVEL OF EVERYTHING JUST NOT LEVEL 2 ONLY. (Comment this)

Written by: WENDY at 2006/08/15 - 13:00:55 in reply to: 17
27 - WENDY, Wendy, I have PCOS and T2 DM. My diagnosis confirmation was about 2 years ago. I take Metformin, which I believe is generic for it. Since I started Byetta, my periods are regular, I'm losing weight all over, not just chest and rear area. Didn't have a clue about Byetta maybe relieving some of PCOS symptoms. Explains the regularity. I suffer from excess hair, especially on my forearms. I am self concious of this because it makes me look less girly. I have noticed a decrease growing back after I nair. Unexpected, but good, side effect I'm just noticing. I would suggest you look up any and everything you can find on Byetta. You'll probably find info your doc doesn't have. I do know thisis possible because as I learn I mention it to my doc and to my surprise, she hadn't a clue. Power on!!! (Comment this)

Written by: Dana Alaska metformin am/noon/pm enalapril glipizide lipitor at 2006/09/19 - 21:29:52 in reply to: 26
28 - I've been diagnosed with PCOS (original diagnosis was Stein-Leventhal Syndrome) for forty years. Originally, it was succesfully treated with a combination of birth control pills and thryoid medication, pretty much eliminating any signs of acne, hirsutism, and weight gain. After twenty years, I had to stop taking both drugs and was switched to Aldactone/Spironolactone which suppressed acne and hirsutism, but my level of testosterone increased, my periods became irregular again, and my weight started to slowly, but steadily increase. When I was diagnosed with diabetes 7 years ago, adding Glucophage/Metformin to the mix seemed to help to reduce my weight but not my testosterone level. After being on Glucophage for 5 years, the weight problem resurfaced and even doubling the dose did little to help me. Finally with Byetta, I have lost all the extra poundage and have watched every three months as my testosterone level reduced with each weight loss. For the first time in forty years, my testosterone is where it should be. I don't think it would be without Byetta enabling me to lose the extra weight. (Comment this)

29 - I have PCOS and ttc and the Dr has me on Metformin and hoping to put me on clomid. If anyone can help and tell me what else I can do to get pregnant e-mail me and the e-mail address up at the top please and thank you. Hope to hear from someone soon..... (Comment this)

Written by: Lynda at 2006/09/26 - 13:32:49
30 - just chiming in... another "Stein-Leventhal" here... been doing the PCOS thang for 20+ years now.

Rezulin was a miracle for me, but they pulled it. Metformin/aka Glucophage helped in the beginning, but the dose gets higher and it has less help.

Yasmin is a miracle, but not covered by insc <grrr> and few samples to be found these days.

Lost 50lbs on Atkins, but then 20g/carbs/day didn't even work at 1200 cals... just 'maintained' for 18 mos or so. Then started realizing how cranky/tired/angry I was all the time. Upped the carbs by just whole grains/fruit adn gained back 10lbs--enough to scare me. 50 more to loose. :(

Started Byetta three weeks ago, seems to be helping the fasting blood sugars/dawn effect. Definitely helping the appetite. Some weight loss, but vuuuuury slow. (1.5 lb/week?) not the 'miracle' of some others. BG's are GREAT though.

Happy to help anyone I can... became a bit of an armchair expert, and have worked with some excellent Docs.

Met & Yasmin are amazing... byetta could be the final link, but too soon to tell. (Comment this)

Written by: jaeme at 2006/10/15 - 21:15:22
31 - Summer, Summer, I see that you are in TN. I'm in my late thirties, have had the dx of PCOS for several years, reactive hypoglycemia for the same and now recently dx with Type II diabetes. In addition, there are the "pesky" symptoms of PCOS (i.e., majorly overweight, acne, etc.).

I'm already on 2000 mg. of Metformin and Yasmin for the PCOS. Too, am on various meds longterm for persistent acne (since teen years)...two different antibiotics (one oral and the other topical) and Finacea. The Yasmin helps with my skin, too. However, I *might* be interested in some other treatment for my skin other than antibiotics. I've been on them pretty much consistently since I was thirteen. Tried a couple of bouts with Accutane, but it didn't work for me. Have some concerns about possible antibiotic resistance, but *every single time* I go off of the antibiotics, I have *huge* flares of cystic acne...very, very troubling and invasive in my life. *Might* want to try some Spironolactone or another approach to the acne.

You mention that you have a great endocrinologist and nutritionist. I am interested in learning the names and locations of both.

Thank you,
Jen (Comment this)

Written by: Jen at 2006/10/19 - 01:27:02 in reply to: 24
32 - Hey anyone else here with PCOS also taking byetta? (Comment this)

Written by: Dawn in GA, PCOS, byetta 5, ziac for bp at 2006/10/23 - 20:49:21
33 - Dear Lahle,
Your experience sounds exactly like mine! I was on the induction phase of Atkins for 5 years and had lost 80 pounds, and then it just stopped working! I slowly gained about 25 pounds back, so I tried and tried for the next 2 years to eat NO carbs, and was at one point down to 300 calories a day for about 3 months, and doing 3 hours of aerobics a day...just to show my snotty unhelpful doc just how hopeless I had become at losing weight, even with extreme dieting and exercise. He just said "try harder!!!" I finally became so depressed that I gave up because friends convinced me that Atkins destroys your metabolism. (also the book The Swartzbine Principle 2 says this, and it is written by an endo who seems to know her stuff)
Later I got a weird lung illness and they put me on Prednisone and I gained 50 pounds in 4 months! I was on Atkins the whole time too! I am now going bald, and had once had beautiful long blonde hair. My skin is covered with warty things and gross bumps, and I have acne and super bad hirsutism. After I had lost the 80 pounds I was soooo happy and wa myself agin, but the magic ended. (I am 5'9 and back up to 265) I almost never leave my house anymore. I feel like my life is over and have been this way for the past 2 years. I am 45.
Have you tried the Byetta? I just want to know if it really helps...is the weight loss from lack of eating, or does it actually change something in the metabolic process with the IR? I hardly eat as it is, so I'm afraid it will be more of the same. I don't know when your letter was originally posted, and hope you can answer my questions. Thanks so much! Andrea
 (Comment this)

Written by: Andrea Pederson at 2006/11/16 - 07:01:04 in reply to: 1
34 - Has anyone gotten pregnant, kept taking metformin while pregnant, and given birth? Is your baby/child healthy? Are there known issues with pregnancy and metformin? I am taking 500mg once a day and we are trying to get pregnant. Thanks. (Comment this)

Written by: Mel at 2006/11/18 - 19:03:23
35 - Andrea Pederson, I'm sorry you are having some problems but you mention The Schwartzbein Principle but don't say if you are following it. Are you? This is the program I've been following for 2 years now and I can't say it's helped completely because it will take time to heal my body but it has helped me alot. My nails are good, my skin is better than ever, my hair is growing like crazy(I never had to get it cut so often before) and it's healthy hair, my body aches less and I generally feel better. My suggestion is read the book again and give the program a 6 mos. try to see what happens. I also take the spit, more for my numbers than for the weight loss. I will never go back to the old way of eating and she is also the one who endorses not eating gluten, which is why I went gluten free(almost) a year ago. (Comment this)

36 - I just found this blog from the Byetta blog. Is there anyone out there reading it. I noticed that the last posting was in Nov of last year. I am interested in if others with PCOS are having any luck lossing weight with Byetta or if the PCOS is helping keep the weight on. I only lost a small amount when I first went on Byetta but have put that back on. (Comment this)

37 - Another question if anyone is listening. I've been on an e-group for PCOS and most on it were younger then me and were dealing with infertility issues. I was lucky enough to have 2 children even with all the problems and didn't know what was causing the problems then. I was past that when I was diagnosed with PCOS after that, but I know it was causing problems then. Now I am menapausal and wondered if there was anyone else out there in this stage of life and knows what changes can be expected as I go through this stage. (Comment this)

38 - Mel,

I have PCOS, only found out b/c I oculdn't get pregnant... although signs were clear no one bothered to tell me... anyways... Did the pregnancy thing with Metformin and now have a healthy boy of 15 months. Good luck with that :) (Comment this)

Written by: Jean at 2007/03/02 - 21:55:40 in reply to: 34
39 - Gloira,

I was dx in my 20s with PCOS. At 40 I had a complete hysterectomy (including both ovaries)due to having a period for a full year. Silly me - thought that would solve the problem of PCOS. Not quite. At the age of 52, i'm still dealing with hirsutism, increasing weight, acne, increase in testosterone levels. Was dx with Type 2 diabetes 5 years ago.

Started Byetta back in July but came off of it due to the nausea and heartburn even though bs were really good - between 80 and 110 consistantly and A1C dropped from 7.4 to 6.1 in 6 weeks. Tried Januvia and Symlin and bs started climing to over 200. Started back on Byetta a couple of weeks ago at the 10 level and having no side effects (strange) but not seeing as good results as before headed down the road of adding metformin in a couple of weeks if the numbers do not come down.

As far as weight loss is concerned, I did have some luck with Symlin - lost 12 lbs in 6 weeks but I have not had any luck with Byetta or Januvia. Very disappointing.

Taking 120mg Sprinolactone 2x a day for the facial hair growth and it has helped - hasn't stopped it completely but it has diminished it.

I am not taking HR since I was not going through any of the menapausal symptoms after surgery - guess I was one of the lucky ones.

I wish you well. Let me know what issues you are experiencing.

 (Comment this)

Written by: Roni - Byetta 10, Starlix 120 2x, Spirnolactone 120 2x at 2007/03/16 - 03:08:16 in reply to: 37
40 - Hi Jean,

How long did it take you to get pregnant once you started taking the Metformin? My endo put me on it a while back and just increased the dose as he noticed my testosterone levels were responding well to the lower dose. He put me on the XR version - and it seems I'm having nausea every morning now. But I take my night dose with food, so I don't know why 8 hours later I'm feeling sick. I'm secretly hoping it's morning sickness, LOL! Did you ever have this problem?

My sister's friend got pregnant on Metformin after only 6 weeks. I'm sure that's not how it works for everyone.

Thanks! (Comment this)

Written by: Melissa at 2007/03/17 - 10:53:28 in reply to: 38
41 - Hello, I was dx w/ pcos several years ago. Metformin made me HORRIBLY ill, to the point that even drinking water made me sick. Right now I weigh more than I ever have in my whole life, and I am miserable in my own body. I've now also started having anxiety attacks, I'm covered with hair and skin tags and wonderful discolored skin (isn't that a pretty picture?) I have been infertile for 8 years now, as I stated, tried the metformin, clomid, low carb, etc. Desperate now, I am curious about Byetta - does it truly help with the weight issues and would it also resolve some of the issues with the cysts and other symptoms? Regaining my fertility would be extra nice as I am 34 now and my clock has slowed waaaay down. My only dilema is that I can only find info on those with type 2 - as of now, I don't have diabetes but actually have some episodes of low blood sugar - help!!

Thanks, you can email me or post responses here! (Comment this)

Written by: kyna at 2007/03/28 - 15:04:16
42 - I'm 38- insulin resistant and have been diagonosed with "all the symptoms of PCOS" but my doctor said she isn't ready to "put that label on me yet". I'm currently taking birth control pills (for the last 3 years) and 1000 mg of glucophage a day. I tried the byetta for a month and lost 12 lbs! I felt wonderful on it- night sweats went away- blood sugar levels great and I had lots of energy. THEN all of the sudden I started getting hives when I'd take a shot. I also had skin reactions to extended release glucophage. My doctor put me on Symlin instead to try and see if I could still benefit from that sort of medicine- it took longer but eventually I started having a reaction to that one too! Has anyone else experienced something similar? I wonder if I could go back on the Byetta and the hives would eventually quit happening? My doctor wants to send me to an allergy specialist, but I'm so frustrated with paying doctors! (Comment this)

Written by: LoLee at 2007/04/19 - 11:00:35
43 - LoLee, I think you could try eating a more alkaline diet to counteract the acid bases of the byetta or other meds. If interested in learning more go to meals, eating, and nutrition island(box #4 to the right) and read page 6, I think it is, about a list of alkaline producing foods. It's worth a try. (Comment this)

44 - KYNA: Have you considered learning more about nutrition and staying away from all the chemicals and hormones in our food supply? Ever since I went organic my skin is clear, my hormones are better, I have more energy. I don't know much about PCOS and byetta but I do know that changing my nutrition and lifestyle has made a bigger difference in my overall health. Weight loss is a side effect of the spit(byetta) so it may or may not help you. I'm losing weight very slowly but it might help you if you combine it with better nutrition. (Comment this)

45 - Some have mentions losing weight with Symlin. What is that? I had not heard of that med. I lost 11 lbs at first on Byetta but have not lost any since. I wondered what the PCOS might have to do with that. Also Menopausal. I was able to go on Byetta with out a lot of bad side effects, but from time to time I find that I feel sick after breakfast. It seems to last a couple of weeks and then stops again for a while. I ended up leaving work last week one day as I was feeling real nausious and light headed. Then got pretty shaky but after I got home and took a glusco tablet to get sugar levels back up the shakiness left. Sugar levels don't usually drop like that with the sick feeling but it did that day. I've had more of those lows since the doctor added 5mg of Glucatrol in the pm because my overall sugar levels had been going up. I was maxed out on the Metformin and the Glucatrol before going on Byetta and was able to drop the Glucatrol way back but have had to gradually add some back on to where I am almost maxed out again. I'm afraid the next step if insulin. I'm afraid insulin will cause more weight gain. I do need to try and watch diet a little better then I do. (Comment this)

46 - Gloria: Byetta in combination with a sulfonylurea is known to cause lows. Amylin even warns about it. It is a good idea to test for lows whenever you feel nauseated. Symlin, by the way, is produced by Amylin, too, and is mostly for type 1 diabetics with little-to-no beta cell activity. I don't know much about PCOS, but if you came over to the Byetta forum, you might get more ideas about making the Byetta work better. Yes, sad to say, diet and exercise still matter. :( (Comment this)

Written by: toneylee at 2007/04/21 - 11:20:11
47 - I am 24, I have PCOS, I have been using the contraceptive Diane35 and also Metformin, I have stopped using it because of the major side effects I have been experiencing. Today I have had my period for almost 3 months as a result of this I am anemic. I have changed my diet to no-carbs and I have increased my iron and vitamin intake. I have done my research and I have learnt that Insulin Resistance is one cause of this condition. Now that we know what the problem is. Why not look for a solution? Which is reversing Insulin Resistance. (Comment this)

Written by: Melissa at 2007/04/23 - 00:11:54
48 - Melissa,
I think there is research going on to find solutions but it often takes a lot of time to find them. For a long time they thought that PCOS was a gynacological problem. That is why the name. Since then they have realized it is a much bigger problem and has to do with insulin. Medications like Metformin often help a lot. A lot of people can not tolerate it though. Mostly they treat the symptoms. A low carb diet is very helpful. No carb in not really good as our bodies get a lot from Carbs also. Energy is one of them. Do all you can to stay as healthy as possible with diet and exercise. Some feel that going as natural as possible with getting organic foods really helps also. Your risks of other illness is greater with PCOS. I've become diabetic in the past 5 years or so. Good Luck with finding help for what you have going on. A good endo can help alot. (Comment this)

49 - I'm 24 years and been having problems with my cycle since the age of 12. A few years later a was diagnosed with PCOS which I been taking birth control pills since the age of 12 to keep me regular. I just started seeing a endo for my PCOS and he is putting me on Metformin to get my insulin level down. He told me I don't have diabetes I'm just taking this medication to get me insulin down, but I'm not so sure about it. He says my insulin affects my kidneys that affects my cycle which is why I'm having irregular bleeding. I don't want to start taking metformin if I don't diabetes, but I do want to get my situation with my cycle resolved. So is it ture that your insulin affects you kidneys that affects my cycle. Please Help!! (Comment this)

Written by: Tyra at 2007/05/21 - 12:21:13
50 - Tyra,
Metformin helps with the insulin resistance often connected with PCOS. If you can take it it will help your insulin work more efficently. I don't know much about helping with your kidneys functioning but if it keeps the insulin working better then it will help in many areas. Low carb diet is also very helpful with regular periods. Diet, exercise and the metformin can help you to stay healthier. PCOS has a high risk of diabetes and diabetes can cause a lot of problems with kidneys and other problems. Best to keep that off as long as possible. Make sure you have doctors that you are comfortable with to discuss what all is going on. Take care and good luck with all of this. (Comment this)

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